Computational biology

Computational biology Home /Biologia integrativa The areas of biotechnology have benefited significantly in recent decades from advances in science and technology which have led to the production of large quantities of data on biological systems. Today, a biological process can be approached considering gene architecture, protein structure and diversity, as well as the diversity of…

Cardiology

Cardiology Home /Biologia integrativa During the first days after birth, the heart exhibits significant regenerative capacity, but the adult heart has limited capacity to regenerate after a heart attack. Because of this difference, researchers at LNBio are focusing on understanding the molecular mechanisms behind the loss of this regenerative capacity in the adult heart in…

Neurodevelopment and multi-scale connectivity

Neurodevelopment and multi-scale connectivity Home /Biologia integrativa The process of neurodevelopment, from the formation of the nervous system to configuration of the neural circuitry, is extremely complex. A multi-scale approach is utilized to understand cerebral plasticity, which is essential for adaptation to environmental demands. This approach includes techniques like multinomics, 3D imaging, and scientific computation…

Biomolecular condensates

Biomolecular condensates Home /Biologia integrativa Biomolecular condensates are composed of proteins and other biomolecules that aggregate in liquid-liquid or liquid-solid structures inside the cells, and perform essential roles in regulating complex biological processes and maintaining cell functions. LNBio stands out in studying the molecular mechanisms of human proteins with critical roles in health and disease.…

Cancer biology

Cancer biology Home /Biologia integrativa Improving the treatment options for diseases like cancer requires continuous evolution of the disease models used in the laboratory. Three-dimensional culture of tumor cells in the form of organoids has proven an important method for establishing personalized therapies. This approach makes it possible to replicate tumors in lab conditions and…