Advanced gene therapy resources
We develop gene therapies using CRISPR/Cas9 to correct mutations, working towards safe and effective therapeutic applications for human genetic diseases that do not yet have medical alternatives
The Advanced Health Technologies division stands out as a driving force in research and development, integrating groups specialized in Pharmaceutical Discovery, Proteomics, Gene Editing, Tissue Engineering, Immunotherapy, and Biologicals. Its main mission is to meet demand from the research and development and innovation (RDI) chain in health, strengthening the health economic industrial complex. Acting as an essential facilitator, the division plays a vital role in carrying out complex tasks, transforming scientific knowledge into practical technologies for the challenges facing the Brazilian health system. Its deliverables cover competencies to produce cell lines that generate monoclonal antibodies, a CRISPR/Cas9 platform to treat genetic diseases, development of artificial organs, proteomics for advanced diagnostics, and innovative pharmaceuticals. These initiatives drive competitiveness and sustainability in the domestic health sector.
We develop gene therapies using CRISPR/Cas9 to correct mutations, working towards safe and effective therapeutic applications for human genetic diseases that do not yet have medical alternatives
We establish scientific and technological competencies for pharmaceutical inputs, including lineages to produce recombinant proteins for innovative medications and biosimilars
We produce recombinant viral vectors for vaccines and advanced therapies, using recombinant DNA technology to modify cells in order to express or silence a molecular target
We deliver drug candidates, driving pharmaceutical innovation in Brazil by combining science and high-tech methods with the unique potential of the innovative chemistry found in Brazilian biodiversity
This group uses proteomics data based on mass spectrometry to discover markers for diagnostics, prognostics, and new targets for diseases such as cancer, for example
Tissue engineering for 3D culture and bioprinting with therapeutic applications and to develop alternatives to animal testing that are robust and mimic in vivo assays
Expanding our understanding of the mechanisms of viral and bacterial illnesses and those that affect neglected populations, such as Chagas disease
Implementing methods for scientific results on the cutting-edge of knowledge, playing a vital role in developing and new experimental approaches and putting them into action
Expanding the understanding of diseases, identifying molecular targets for personalized therapies, and translating discoveries into health benefits