This facility makes it possible to conduct biophysical studies of macromolecules, nanoparticles, and polymers in solution. Providing information about structure, coiling, molecular binding, dissociation constants, stability, size, shape, and oligomeric state
Nuclear magnetic resonance is an alternative technique that is widely used to resolve the atomic structure of proteins, particularly those with low molecular weights which do not form crystals
Proteomics based on state-of-the-art mass spectrometry for CNPEM’s internal and external users. The MAS lab comprises the sample preparation lab, the instrumentation lab, and the data analysis lab
Projeto do CNPEM com universidade holandesa disponibiliza bolsa de PD em Engenharia de Tecidos O Centro Nacional de Pesquisa em Energia e Materiais (CNPEM), em parceria com o Radboud University Medical Center (Radboudumc), nos Países Baixos, dispõe de uma vaga de pós-doutorado, com apoio da Fundação de Amparo à Pesquisa do Estado de São Paulo…
Trabalho realizado no Centro busca suprir demanda nacional interna, tanto de testes de toxicidade de fármacos e cosméticos como opção alternativa aos testes com animais, quanto de produção própria de curativos com células humanas, que não podem ser importados
Formulation of innovative therapeutic strategies based on viral vectors, nanoparticles, chimeric aptamers and monoclonal antibodies. This group has expertise in the production of vectors derived from retroviruses, lentiviruses, adenoviruses and adeno-associated viruses, and can also generate cell banks that produce human monoclonal antibodies, known as research cell banks (RCB)
This center uses innovative biomaterial formulations and bioprinting technologies to develop 3D cell models. It focuses on creation of in vitro models as alternatives to animal testing and on progress in advanced therapies, with emphasis on the development of biodressings
This center is dedicated to establishing gene therapy strategies using CRISPR/Cas9, base editing and prime editing to treat diseases that still do not have cures. The team has also been working to optimize encapsulation and delivery of these advanced therapy products (ATP) to develop safer and more effective treatments
This center develops mass spectrometry proteomics methods to identify and quantify proteins and peptides, including spatial, structural, single-cell and computational proteomics. The work focuses on discovery and validation of molecular signatures with diagnostic, prognostic and therapeutic potential that are aligned with precision medicine and health innovation
