Drug Discovery

Drug Discovery

The work of the Drug Discovery Division spans from generating the biological hypothesis for pharmaceutical innovation to obtaining the candidate drug. Its mission is to drive radical innovation in pharmaceuticals in Brazil, through sustainable use of biodiversity in synergy with cutting-edge science and advanced technology. It uses a drug discovery platform that incorporates structural biology; bioassays; natural product biotechnology; natural product, medicinal and synthetic chemistry; as well as advanced computing. This integration allows the generation of customized experimental and computational methods for drug discovery and development of new bioactive compounds.

Within this context, the group leads drug discovery projects that accelerate TRLs 2-4, fostering interactions between ICTs, local communities and industry (from startups to large companies) in networks linked to the platform. This also guides the innovation ecosystem towards solving national challenges, such as consolidating the knowledge economy and strengthening pharmaceutical innovation as pillars of ecological transition and One Health in Brazil. Its values include social, regional and technological inclusion, aligning local vocations with national and global health demands.

meet our groups

meet our team

Daniela B. B. Trivella

Division leader and researcher

Alisson Campos Cardoso

Lead Researcher

Rafael de Felício

Lead Researcher

Marjorie C. P. Bruder

Lead Researcher

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Expanding the understanding of diseases, identifying molecular targets for personalized therapies, and translating discoveries into health benefits

Implementing methods for scientific results on the cutting-edge of knowledge, playing a vital role in developing and new experimental approaches and putting them into action

Expanding our understanding of the mechanisms of viral and bacterial illnesses and those that affect neglected populations, such as Chagas disease

Enables radical innovation in pharmaceuticals in Brazil through the sustainable use of biodiversity in connection with cutting-edge science and high technology