The Integrative Biology Division at LNBio works to investigate the fundamental mechanisms of life through a multidimensional and collaborative approach that integrates biological organization on different scales ranging from molecular structure to cell and tissue function. The research groups are committed to generating fundamental knowledge and promoting innovations that will help us face challenges to human health.
This division comprises research groups with complementary areas of expertise: Computational Biology, Non-Membrane Organelles, Protein Design, Nuclear Structure and Molecular and Cellular Sociology. Together, these groups form an integrated and highly interdisciplinary unit that combines state-of-the-art experimentation, computational modeling and technological innovation to construct bridges between different areas of bioscience and make discoveries with the potential to transform biomedical knowledge and its applications.
Investigates molecular and cellular interactions in living tissue, with a focus on metabolic adaptation, tumor immunosuppression and development of personalized therapies
Investigates the formation, function and regulation of biomolecular condensates formed by phase separation, with direct impacts in the understanding of genomic regulation and metabolism
Works to reveal the three-dimensional structure of the genome and its relationship to gene expression and essential cellular processes
This group focuses on engineering proteins with specific properties, for applications in biotechnology, therapies, and to study molecular mechanisms
Expanding our understanding of the mechanisms of viral and bacterial illnesses and those that affect neglected populations, such as Chagas disease
Implementing methods for scientific results on the cutting-edge of knowledge, playing a vital role in developing and new experimental approaches and putting them into action
Acting as a catalyst and carrying out complex tasks, transforming scientific knowledge into technologies for Brazilian healthcare
Enables radical innovation in pharmaceuticals in Brazil through the sustainable use of biodiversity in connection with cutting-edge science and high technology