The Integrative Biology Division is a multifaceted structure comprised of research groups specializing in studies on the molecular, cellular, and physiological foundations of critical areas such as cancer, neurodevelopment, and cardiology. This division is driven by a unified mission: to understand the mechanisms underlying various diseases in order to identify and assess potential molecular targets to develop new therapies. The ultimate goal is to translate these discoveries into tangible benefits for human health with the introduction of more effective and personalized therapies.
Dedicated to the study of molecular mechanisms associated with intellectual impairment, investigating mutations and the impact on the nervous system to improve diagnostics and treatments
Investigating the molecular foundations of cancer, studying its development in natural microenvironments
Design de proteínas Home /Scientific divisions/Integrative biology/Cancer biology A possibilidade de expandir o universo conhecido de sequências de aminoácidos de proteínas, por meio do design de novo ou da engenharia de proteínas, viabiliza desde a otimização de propriedades de proteínas já existentes até a criação de proteínas com novas funções e estruturas, com ampla aplicabilidade…
Estrutura nuclear Home /Scientific divisions/Integrative biology/Cancer biology O Grupo de Estrutura Nuclear do LNBio/CNPEM nasce com a missão de desvendar como a organização física do genoma influencia seu funcionamento — e, por consequência, a saúde celular. Utilizando tecnologias de ponta em microscopia, biologia estrutural e modelagem, o grupo busca entender como o DNA se dobra,…
Working to improve heart failure through therapies that regenerate cardiomyocytes, using advanced analytical and imaging techniques
Develops precise computational models to understand biomacromolecular systems, accelerating the production of experimental findings
Expanding our understanding of the mechanisms of viral and bacterial illnesses and those that affect neglected populations, such as Chagas disease
Implementing methods for scientific results on the cutting-edge of knowledge, playing a vital role in developing and new experimental approaches and putting them into action
Acting as a catalyst and carrying out complex tasks, transforming scientific knowledge into technologies for Brazilian healthcare