Biological Data Home /Scientific divisions/Page 3 This team works together with LNBio’s research groups, offering a robust computational infrastructure for high-performance processing of biological data. It conducts advanced statistical analyses, applies techniques for visualization and processing of bioimages, along with methods from bioinformatics, machine learning, and artificial intelligence. The objective of these approaches is to…
Advanced Methods in Biology Home /Scientific divisions/Page 3 Advanced Methods in Biology The bioimaging, advanced omics and biological data groups offer tools to advance modern biology. Bioimaging allows high-resolution visualization of biological structures and processes at the molecular, cellular, and tissue level, revealing details about the dynamics and function of these systems. Advanced omics represents…
Applied Chromatography Laboratory (LCA) Home /Scientific divisions/Page 3 This team works to develop pre-analytical and analytical technologies to identify, qualify, and quantify small molecules, focused on liquid chromatography associated with spectroscopic and spectrometric techniques. It develops specific metabolic profiles in biological samples and identifies and quantifies targets in complex mixtures. It also carries out and…
Biomolecules Home /Scientific divisions/Page 3 Biomolecules The Biomolecules Group is dedicated to chemical synthesis of oligonucleotides and peptides, as well as the production, purification, biophysical characterization and crystallization of proteins and their complexes. Comprising four highly specialized and well-equipped laboratories, the group is strategic for the scientific community, integrating essential technologies for interaction studies, structural,…
Protein Purification Laboratory Home /Scientific divisions/Page 3 LNBio has a complete structure for the production of recombinant proteins in heterologous systems, such as bacteria and insect cells. Currently, it offers academic users all the experience, structure, supplies and equipment for the complete production process using bacteria, from E. coli transformation to recombinant protein expression, purification…
Facilities and services Home /Scientific divisions/Page 3 Facilities and services The mission of LNBio’s Facilities and Services Division is to promote scientific and technological excellence by providing strategic reference laboratories, supporting CNPEM researchers and the external academic community in innovative projects. This division plays a fundamental role in executing, refining, and developing new technologies, expanding…
Immunotherapy Technology Center (NuTI) Home /Scientific divisions/Page 3 Immunotherapy is a clinical mode of treating cancer that complements conventional therapies like surgery, radiation therapy, and chemotherapy. While surgery and radiotherapy are used for local treatment, chemotherapy and immunotherapy are applied systematically. Chemotherapy blocks non-specific mechanisms associated with cell division, while immunotherapy stimulates the immune system…
Biologicals Home /Scientific divisions/Page 3 Medications derived from biotechnological processes have revolutionized therapeutic strategies for various diseases. Recombinant proteins like the monoclonal antibodies used to treat cancer, for example, are produced in cell lines. These, in turn, must be established in laboratory structures that are equipped to construct vectors for expression, cell transfection, selection of…
Tissue Engineering Technology Center (NuTET) Home /Scientific divisions/Page 3 The Tissue Engineering Technology Center (NuTET) develops innovative tissue engineering solutions with a focus on regeneration, replacement and repair of human tissues. Using technologies like 3D bioprinting and microphysiological systems, NuTET’s activities range from formulation of biomaterials to creating three-dimensional cell cultures, with applications in regenerative…
Gene Editing Technology Center (NuTEG) Home /Scientific divisions/Page 3 Gene therapy is an innovative treatment and one component of what are known as advanced therapy products (ATP). For more than a decade this area has been evolving worldwide, bringing promising advances in the treatment of human diseases. In late 2023, regulatory agencies in the US…