Protein purification Home /Scientific divisions/Page 2 LNBio has a complete structure for the production of recombinant proteins in heterologous systems, such as bacteria and insect cells. Currently, it offers academic users all the experience, structure, supplies and equipment for the complete production process using bacteria, from E. coli transformation to recombinant protein expression, purification and…
Facilities and services Home /Scientific divisions/Page 2 Facilities and services The mission of LNBio’s Facilities and Services division is to incorporate methods to produce essential information and attain outstanding scientific results. This division plays a fundamental role in executing, refining, and developing experimental approaches, expanding laboratory infrastructure, and encouraging research innovation. With a new modern…
We produce recombinant viral vectors for vaccines and advanced therapies, using recombinant DNA technology to modify cells in order to express or silence a molecular target
Cancer immunotherapies Home /Scientific divisions/Page 2 Immunotherapy is a clinical mode of treating cancer that complements conventional therapies like surgery, radiation therapy, and chemotherapy. While surgery and radiotherapy are used for local treatment, chemotherapy and immunotherapy are applied systematically. Chemotherapy blocks non-specific mechanisms associated with cell division, while immunotherapy stimulates the immune system to strengthen…
We establish scientific and technological competencies for pharmaceutical inputs, including lineages to produce recombinant proteins for innovative medications and biosimilars
Biologicals Home /Scientific divisions/Page 2 Medications derived from biotechnological processes have revolutionized therapeutic strategies for various diseases. Recombinant proteins like the monoclonal antibodies used to treat cancer, for example, are produced in cell lines. These, in turn, must be established in laboratory structures that are equipped to construct vectors for expression, cell transfection, selection of…
Tissue engineering for 3D culture and bioprinting with therapeutic applications and to develop alternatives to animal testing that are robust and mimic in vivo assays
Tissue engineering Home /Scientific divisions/Page 2 Tissue engineering looks for alternatives to transplants, developing materials to replace, repair, or regenerate defective tissues, overcoming challenges such as limited organ availability and chronic rejection. The group works to develop therapies using biofabricated tissues that can be applied in cardiac and dermatological dressings. In Brazil, LNBio is one…
We develop gene therapies using CRISPR/Cas9 to correct mutations, working towards safe and effective therapeutic applications for human genetic diseases that do not yet have medical alternatives
Advanced gene therapy resources Home /Scientific divisions/Page 2 Gene therapy is part of an innovative class of treatments known as advanced therapy medicinal products (ATMPs), which has been developing internationally for over a decade and has demonstrated scientific and technological advances that are favorable for treating hematological and ocular diseases and some types of cancer.…