In order to guarantee the high degree of purity and homogeneity required for biophysical and functional analyses, LNBio has a Protein Purification Laboratory (LPP), equipped with several semi-automated chromatographs that enable the main liquid chromatography techniques to be carried out
The Biomolecule Synthesis Laboratory emerged to provide institutional independence in obtaining certain types of biomolecules. Being able to generate raw materials on site provides speed and flexibility in the production of biomolecules for different types of research and applications
High-throughput screening (HTS) is a scientific experimentation technique that makes it possible to conduct automated biochemical or cellular assays on thousands of chemical samples, from synthetic or natural sources, using the smallest possible quantities of reagents
Advanced methodologies have revolutionized our understanding of biological processes in health and in illnesses, offering new opportunities for early diagnosis, to develop personalized therapies, and to discover prognostic biomarkers
Bioassays laboratory Home /Scientific divisions The Bioassays Laboratory has staff and infrastructure dedicated to conducting automated biochemical and cellular experiments to identify bioactive molecules via high-yield screening methods. Biochemical assays generally assess the activity of a target protein using fluorescence spectroscopy techniques, while cell assays attempt to identify changes in the phenotype of a cell…
Biological data Home /Scientific divisions This team works together with groups and users to offer a robust computational infrastructure for high-performance processing of biological data. It conducts advanced statistical analyses and applies visualization techniques and methods from bioinformatics, machine learning, and artificial intelligence. The objective of these approaches is to extract significant information about sets…
Advanced methods in biology Home /Scientific divisions Advanced methods in biology The bioimaging and bioinformatics groups offer important tools to advance modern biology. Bioimaging acts as a powerful lens that provides a high-resolution view of biological structures and processes at the molecular, cellular, and tissue levels, revealing details about the dynamics and function of these…
Chromatography Analysis of Small Molecules (LAMP-C) Home /Scientific divisions This team works to identify and quantify targets in complex mixtures, and develops specific metabolic profiles in biological samples. It carries out and analyzes various ADME tests in vitro such as those to determine solubility and stability and chromatographic logP and logD. It also conducts in…
Biomolecules Home /Scientific divisions Biomolecules The work of this group ranges from the synthesis to the characterization of biomolecules, using advanced techniques and high-throughput equipment to prepare, crystallize, and purify samples. Comprised of four highly specialized laboratories, the Biomolecules group is a strategic resource for the scientific community, incorporating essential technologies for interaction studies and…
Protein purification Home /Scientific divisions Attention to deadlines LPP will accept proposal submissions from December 10, 2024, to January 15, 2025. Please note that the facility will not be available to receive research proposals before this period. LNBio has a complete structure for the production of recombinant proteins in heterologous systems, such as bacteria and…