Integration
The division connects Brazil via molecules, advanced methods and innovation initiatives, with global impact and local co-development
Medicinal Chemistry
Develops molecules with properties suitable for proving efficacy in animal models, an essential step in pharmaceutical development
Molecular Pharmacology
Large-scale search for bioactive molecules through biochemical and cellular assays, integrative structural biology and biotechnology applied to drug discovery and development
Natural Products
This group promotes the advancement of knowledge related to the chemistry of natural products through the development and application of innovative pipelines with a focus on discovering new drugs and preserving Brazil’s biodiversity
Target Discovery and Validation
Identifying therapeutic targets with the objective of developing new treatments for human diseases
Integration
Integration Home /Scientific divisions Manages drug discovery projects and partnerships with ICTs, manufacturers and local communities. Develops advanced computational methods for organizing and mining data in drug discovery. Coordinates and participates in network projects such as IFA-BR (FINEP Mais Inovação Saúde), Cadeias Produtivas Licuri (MTI/FINEP) and Iwasa’i (CNPq Pro-Amazonia). The group is responsible for managing…
Medicinal Chemistry
Medicinal Chemistry Home /Scientific divisions Develops molecules with properties suitable for pharmaceutical candidates with efficacy in animal models, an essential step in pharmaceutical development. Medicinal chemistry approaches are adopted for rational planning of new pharmaceutically active chemical substances. This work is guided by the analysis of bioassay results and the prediction of drug properties, and…
Molecular Pharmacology
Molecular Pharmacology Home /Scientific divisions Bioassays are used to evaluate large collections of molecules and select starting molecules for drug discovery projects. Highlights include structural biology approaches and biochemical, biophysical and cellular assays in high-throughput screening, as well as testing various cell types, including immortalized cells and human models derived from stem cells in two-dimensional…
Natural Products
Natural Products Home /Scientific divisions The Natural Products Group promotes the advancement of knowledge related to the chemistry of natural products through the development and application of innovative pipelines with a focus on discovering new drugs and preserving Brazil’s biodiversity. Through partnerships with companies and academia, the group’s main activities focus on: a) building libraries…
Target Discovery and Validation
Target Discovery and Validation Home /Scientific divisions The Target Discovery and Validation research group focuses on identifying and validating therapeutic targets in order to develop new treatments for human diseases. The process begins with research to understand the molecular mechanisms of diseases such as neurodegenerative, cardiovascular, and metabolic disorders as well as cancer, selecting and…