Biological Imaging Laboratory

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About the facility

With a strategic role supporting research in life sciences, the Biological Imaging Laboratory (LIB) offers advanced solutions in cellular and subcellular imaging, with a focus on fluorescence microscopy and super-resolution techniques. The facility combines state-of-the-art infrastructure with qualified technical expertise, contributing to the generation of quantitative and visually resolutive data in various biological models.

The facility is equipped with confocal microscopes and super-resolution microscopes based on stimulated emission depletion (STED). The team is directly involved in training and supporting users, promoting the dissemination of good practices in microscopy and contributing to the methodological development of complex projects.

LIB also actively participates in national and international initiatives aimed at training and integrating imaging platforms, positioning itself as a reference center in Brazil for application and expansion of the use of advanced optical techniques in cell, molecular and structural biology.

How to submit research proposals

Academic researchers interested in conducting experiments using STED and confocal microscopy can submit their proposals through the SAU. Proposals for experiments are valid for one year and can be submitted at any time during the year. LIB offers complete scientific support ranging from experimental planning and the choice of analysis method to conducting assays, user training and preliminary data analysis.

To use LIB, you must submit a proposal via SAU Online. If you have any questions, please contact CNPEM’s User Office at edu@cnpem.br or the team responsible for the facility at coordenadoreslib@lnbio.cnpem.br.

Equipment

  • Leica TCS SP8 confocal microscope;
  • STED TCS SP8 Leica super-resolution microscope;
  • DM6 Leica vertical brightfield and fluorescence microscope.

Main competencies and techniques

  • Acquisition of images by conventional, confocal and super-resolution fluorescence microscopy (STED) in the deep red range (590 nm–650 nm);
  • 2D and 3D imaging of fixed samples;
  • Processing and quantitative analysis of images with tools such as FIJI and Cell Profiler;
  • Support for experimental design in bioimaging projects;
  • User training and qualification in advanced microscopy.

meet our team

Juliana Ferreira Oliveira

Lead Researcher (Interim)

Thayná Mendonça Avelino

Researcher

Stephanie Silva Santos

Specialist

Pablo Wesley De Aguiar E Silva

Analyst