Applied Chromatography Laboratory (LCA)

This team works to develop pre-analytical and analytical technologies to identify, qualify, and quantify small molecules, focused on liquid chromatography associated with spectroscopic and spectrometric techniques. It develops specific metabolic profiles in biological samples and identifies and quantifies targets in complex mixtures. It also carries out and analyzes in vitro ADME experiments that study aspects including solubility, stability, and chromatographic logP and logD. It also conducts in vivo experiments for a wide-ranging assessment of ADME (absorption, distribution, metabolism, and excretion), ensuring complete understanding of the pharmacokinetic profile.