Molecular Pharmacology

Bioassays are used to evaluate large collections of molecules and select starting molecules for drug discovery projects. Highlights include structural biology approaches and biochemical, biophysical and cellular assays in high-throughput screening, as well as testing various cell types, including immortalized cells and human models derived from stem cells in two-dimensional (neurons and neural progenitors) and three-dimensional (neural organoids) modalities. Along with molecular biology tools, this group uses biotechnological routes to prospect for molecules of pharmaceutical interest.