Seminar: “Modern Analytical Ultracentrifugation in the Analysis of Macromolecular Interactions”

Informações Data: 04/03/2013 – 00:00:00 Fim: 08/03/2013 – 23:59:59 Onde: CNPEM – Rua Giuseppe Máximo Scolfaro, 10.000 – Campinas, SÃO PAULO 13280000 Brazil – Telefone: 19 35121267 Detalhes LNBio will host, between the 4th and 8th of March, the Workshop “Thermodynamic Analysis of Macromolecules in Solution – Learning and SEDFIT SEDPHAT” The event will be…

Seminar: "Applications of NMR Spectroscopy to Biotechnology at LNBio – Recent and future projects"

Informações Data: 11/03/2013 – 08:30:00 Fim: 11/03/2013 – 17:00:00 Onde: CNPEM – Rua Giuseppe Máximo Scolfaro, 10.000 – Campinas, SÃO PAULO 13280000 Brazil – Telefone: 19 35121267 Detalhes An overview of the current projects and collaborations of the LNBio Nuclear Magnetic Resonance Facility team will be presented, focusing on  projects involving structures of proteins and…

Seminar: "How bacterial TAL effectors modulate specific targets in the host cells to cause plant diseases"

Informações Data: 18/03/2013 – 08:30:00 Fim: 18/03/2013 – 17:00:00 Onde: CNPEM – Rua Giuseppe Máximo Scolfaro, 10.000 – Campinas, SÃO PAULO 13280000 Brazil – Telefone: 19 35121267 Detalhes TAL effectors are bacterial proteins that function as transcriptional activators in the plant cell. In this seminar, we will present how TAL effectors from the citrus canker…

Seminar: “Disruption of prion protein-HOP engagement impairs glioblastoma growth and cognitive decline and improves overall survival”

Informações Data: 25/03/2013 – 08:30:00 Fim: 25/03/2013 – 17:00:00 Onde: CNPEM – Rua Giuseppe Máximo Scolfaro, 10.000 – Campinas, SÃO PAULO 13280000 Brazil – Telefone: 19 35121267 Detalhes Glioblastomas (GBMs) are resistant to current therapy protocols and identification of molecules that target these tumors is crucial. Interaction of secreted Hsp70-Hsp90 organizing protein (HOP) with cellular…

Seminar: “Modulating the reactivity of the proteasome with natural product based inhibitors”

Informações Data: 01/04/2013 – 08:30:00 Fim: 01/04/2013 – 17:00:00 Onde: CNPEM – Rua Giuseppe Máximo Scolfaro, 10.000 – Campinas, SÃO PAULO 13280000 Brazil – Telefone: 19 35121267 Detalhes Proteasome inhibition is clinically validated as chemotherapy and is highly restricted to a select group of electrophiles. In this talk will be presented the molecular basis of…

Seminar: “The role of members of Nek family kinases in the regulation of mitotic progression and in the DNA damage response”

Informações Data: 08/04/2013 – 08:30:00 Fim: 08/04/2013 – 17:00:00 Onde: CNPEM – Rua Giuseppe Máximo Scolfaro, 10.000 – Campinas, SÃO PAULO 13280000 Brazil – Telefone: 19 35121267 Detalhes The founding member of the kinases Nek family (NIMA related kinase) is the protein NIMA (Never in mitosis A) of Aspergillus nidulans. The loss of its function…

Seminar: “Fragment-based methods for drug discovery and chemical biology”

Informações Data: 15/04/2013 – 08:30:00 Fim: 15/04/2013 – 17:00:00 Onde: CNPEM – Rua Giuseppe Máximo Scolfaro, 10.000 – Campinas, SÃO PAULO 13280000 Brazil – Telefone: 19 35121267 Detalhes We have developed several approaches based on different biophysical methods to identify low affinity fragments binding to macromolecules. These fragments act as starting points for subsequent elaboration…

Seminar: "Origins of the vertebrate heart: a paleontological study of the cardiovascular system from the Araripe basin".

Informações Data: 22/04/2013 – 08:30:00 Fim: 22/04/2013 – 17:00:00 Onde: CNPEM – Rua Giuseppe Máximo Scolfaro, 10.000 – Campinas, SÃO PAULO 13280000 Brazil – Telefone: 19 35121267 Detalhes An important aaproach to test the various hypotheses about the origin of the vertebrate chambered heart would be the analysis of the fossil record, especially from animals…

Seminar: "In silico prediction of macromolecular complexes"

Informações Data: 06/05/2013 – 08:30:00 Fim: 06/05/2013 – 17:00:00 Onde: CNPEM – Rua Giuseppe Máximo Scolfaro, 10.000 – Campinas, SÃO PAULO 13280000 Brazil – Telefone: 19 35121267 Detalhes Proteins are prodigal molecules in binding to other chemical entities, either organic or inorganic; these interactions are mostly related to the diversity of organic radicals neatly distributed in the space by thermodynamicallyfolding of the polypeptide chain. This spatial organization allows either the…