Spectroscopy and Calorimetry
The Spectroscopy and Calorimetry Facility was set up in 2002, as central resource to study proteins biophysics, and is part of the biophysical target-characterization platform at LNBio. It houses instrumentation to study macromolecules, nanoparticles and polymers in solution, providing different devices as spectrophotometer, fluorimeter, circular dichroism, isothermal titration calorimetry, differential scanning calorimetry, analytical ultracentrifugation, microscale thermophoresis, dynamic light scattering, GPC/SEC (or SEC-MALS), multimode plate reader, isoelectric focusing and native electrophoresis. Our scientific mission is to develop and optimize methods to study macromolecular interactions, dynamics and stability.
This facility is fully capable of providing information on structure, folding, ligand binding dissociation constants and association kinetics, stability and oligomeric states of macromolecules. Additionally, it owns capabilities for molecular weight, zeta potential, shape, and conformation of biological macromolecules, some polymers and nanoparticles measurements.
Our staff provides training, tips for sample preparation and instrument access for all researches. The facility works from Monday to Friday, from 8 a.m. to 5 p.m.