Informações
Data: 27/05/2013 – 08:30:00
Fim: 27/05/2013 – 17:00:00
Onde: CNPEM – Rua Giuseppe Máximo Scolfaro, 10.000 – Campinas, SÃO PAULO 13280000 Brazil – Telefone: 19 35121267
Detalhes
Marine invertebrates and microorganisms have been the subject of much interest during the past decades due to their production and/or accumulation of structurally unique metabolites with potent biological activities.
Our research group has invested increasing efforts in the discovery of secondary metabolites from sponges, ascidians, bryozoans, octocorals, bacteria and fungi of marine origin, which have shown to be active in anti-leishmaniasis, cytotoxicity, anti-inflammatory, anti-microbial and anti-viral bioassays. Several classes of bioactive metabolites have been discovered, such as alkaloids, steroids, polyketides and terpenes.
More recently, our group initiated efforts to develop methodologies aimed at to investigate alternatives for growth optimization of marine microorganisms in order to produce bioactive metabolites. The use of various culture media and the optimization by experimental design approaches have been continuously investigated, leading to the isolation of structurally unique secondary metabolites produced by marine fungi.
Finally, recently we have started to investigate the biosynthetic pathways of secondary metabolites production by marine fungi in order to better understand how these substances are formed during the metabolism of these microorganisms.
Speaker: Dr. Roberto G. S. Berlinck – Instituto de Química de São Carlos, USP
27th May at 8:30am
Sala 69 – LNBio
Campus – Centro Nacional de Pesquisa em Energia e Materiais – CNPEM
Rua Giuseppe M. Scolfaro, 10.000 – Guará
Telefone: (19) 3512-1010
