Arquivo Anual: 2015

Symposium: Advances and limitations in drug discovery for trypanosomiases and leishmaniasis

Informações Data: 06/05/2013 – 14:00:00 Fim: 06/05/2013 – 17:00:00 Onde: CNPEM – Rua Giuseppe Máximo Scolfaro, 10.000 – Campinas, SÃO PAULO 13280000 Brazil – Telefone: 19 35121267 Detalhes Tropical neglected diseases are a group of diseases that affect underprivileged populations and are characterized by the lack of pharmaceutical R&D investments. In this group, leishmaniasis and…

Seminar: “Proteomics of Tumor Microenvironment: Potential Roles in Carcinogenesis, Tumorigenesis and Metastasis”.

Informações Data: 14/05/2013 – 08:30:00 Fim: 14/05/2013 – 17:00:00 Onde: CNPEM – Rua Giuseppe Máximo Scolfaro, 10.000 – Campinas, SÃO PAULO 13280000 Brazil – Telefone: 19 35121267 Detalhes Speaker: Dr. Jay W. Fox – University of Virginia 14th May at 8:30am LNBio – Room 69 Campus – Centro Nacional de Pesquisa em Energia e Materiais…

Seminar: "The mTOR kinase pathway in cancer development and heart failure."

Informações Data: 20/05/2013 – 08:30:00 Fim: 20/05/2013 – 17:00:00 Onde: CNPEM – Rua Giuseppe Máximo Scolfaro, 10.000 – Campinas, SÃO PAULO 13280000 Brazil – Telefone: 19 35121267 Detalhes mTOR is a conserved kinase that integrates several stimuli, such as growth factors, stress, energy levels and nutrients, especially branched chain aminoacids, to regulate cellular metabolism and growth. The most studied substrates of mTOR kinase are S6K and 4E-BP, an inhibitor of the translation initiation factor eIF4E. mTOR regulates translation initiation by the phosphorylation of these two substrates.The dysregulation of mTOR kinase is related…

Seminar: "Structural Studies, Biosynthesis and Biological Activities of Secondary Metabolites from Marine Organisms".

Informações Data: 27/05/2013 – 08:30:00 Fim: 27/05/2013 – 17:00:00 Onde: CNPEM – Rua Giuseppe Máximo Scolfaro, 10.000 – Campinas, SÃO PAULO 13280000 Brazil – Telefone: 19 35121267 Detalhes Marine invertebrates and microorganisms have been the subject of much interest during the past decades due to their production and/or accumulation of structurally unique metabolites with potent…

Seminar: "Translational research and drug discovery for human trypanosomiases and leishmaniasis: strategies based on phenotypic assays."

Informações Data: 03/06/2013 – 08:30:00 Fim: 03/06/2013 – 17:00:00 Onde: CNPEM – Rua Giuseppe Máximo Scolfaro, 10.000 – Campinas, SÃO PAULO 13280000 Brazil – Telefone: 19 35121267 Detalhes Tropical neglected diseases are a group of diseases that affect underprivileged populations and are characterized by the lack of pharmaceutical R&D investments. In this group, leishmaniasis and…

Seminar: “Myocardial tissue remodeling: not just what meets the eye!”

Informações Data: 13/06/2013 – 08:30:00 Fim: 13/06/2013 – 17:00:00 Onde: CNPEM – Rua Giuseppe Máximo Scolfaro, 10.000 – Campinas, SÃO PAULO 13280000 Brazil – Telefone: 19 35121267 Detalhes Speaker: Dr. Michael Jerosch-Herold – Director of Cardiac MR Imaging Physics, Brigham & Women’s Hospital – Professor of Radiology, Brigham & Women’s Hospital – Harvard Medical School 13th June at 8:30am Sala…

Seminar: "In silico docking of small molecules"

Informações Data: 01/08/2013 – 08:00:00 Fim: 01/08/2013 – 17:00:00 Onde: CNPEM – Rua Giuseppe Máximo Scolfaro, 10.000 – Campinas, SÃO PAULO 13280000 Brazil – Telefone: 19 35121267 Detalhes Computational molecular docking is a well-established technique that provides a structural conformation and interaction energy between two molecules. This prediction is done using algorithms such as Monte…

Functional and structural studies of ABC transporters: pathogenesis and drug resistance"

Informações Data: 12/08/2013 – 08:30:00 Fim: 12/08/2013 – 17:00:00 Onde: CNPEM – Rua Giuseppe Máximo Scolfaro, 10.000 – Campinas, SÃO PAULO 13280000 Brazil – Telefone: 19 35121267 Detalhes Speaker: Dr. Michael Jerosch-Herold – Director of Cardiac MR Imaging Physics, Brigham & Women’s Hospital – Professor of Radiology, Brigham & Women’s Hospital – Harvard Medical School 13th June at 8:30am Sala…

Seminar: Active Glutaminase C self-assembles into a supra-tetrameric oligomer which can be disrupted by an allosteric inhibitor

Informações Data: 12/08/2013 – 08:30:00 Fim: 12/08/2013 – 17:00:00 Onde: CNPEM – Rua Giuseppe Máximo Scolfaro, 10.000 – Campinas, SÃO PAULO 13280000 Brazil – Telefone: 19 35121267 Detalhes Abstract: The phosphate-dependent transition between enzimatically inert dimers into catalytically-capable tetramers has long been the accepted mechanism for the glutaminase activation. Here, we demonstrate that activated Glutaminase…

Seminar: Thyroid hormones: Mechanisms of action and receptor regulation

Informações Data: 26/08/2013 – 08:30:00 Fim: 26/08/2013 – 17:00:00 Onde: CNPEM – Rua Giuseppe Máximo Scolfaro, 10.000 – Campinas, SÃO PAULO 13280000 Brazil – Telefone: 19 35121267 Detalhes Abstract: The Thyroid Hormone Receptors (TRs) are members of the nuclear receptors superfamily, which act as transcription regulators modulated by ligand binding. The regulation of these proteins…