Seminar: Active Glutaminase C self-assembles into a supra-tetrameric oligomer which can be disrupted by an allosteric inhibitor
Informações Data: 12/08/2013 – 08:30:00 Fim: 12/08/2013 – 17:00:00 Onde: CNPEM – Rua Giuseppe Máximo Scolfaro, 10.000 – Campinas, SÃO PAULO 13280000 Brazil – Telefone: 19 35121267 Detalhes Abstract: The phosphate-dependent transition between enzimatically inert dimers into catalytically-capable tetramers has long been the accepted mechanism for the glutaminase activation. Here, we demonstrate that activated Glutaminase…