Abstract: Natural product chemicals have historically been discovered based on their molecular and biological properties. With the ease and affordability of genome sequencing today, a new era in natural product discovery is unfolding in which genomics and biosynthesis are together fostering new innovations in compound discovery. This orthogonal discovery approach takes advantage of the biosynthetic potential of a genome-sequenced organism to design hypothesis-driven experiments to uncover new chemical entities. Examples from the author’s laboratory will highlight the myriad of available and evolving genome mining approaches to new natural product chemistry and biosynthetic enzymology.

Speaker: Dr. Bradley S. Moore – Scripps Institution of Oceanography and Skaggs School of Pharmacy and Pharmaceutical Sciences, UCSD

7th November at 9:00 am

Room 69 – LNBio
Campus – Centro Nacional de Pesquisa em Energia e Materiais – CNPEM
Rua Giuseppe M. Scolfaro, 10.000 – Guará
Tel: (19) 3512-1010