{"id":54592,"date":"2025-02-13T09:19:35","date_gmt":"2025-02-13T12:19:35","guid":{"rendered":"https:\/\/lnbio.cnpem.br\/?page_id=54592"},"modified":"2025-02-13T09:19:35","modified_gmt":"2025-02-13T12:19:35","slug":"nuclear-magnetic-resonance-laboratory","status":"publish","type":"post","link":"https:\/\/lnbio.cnpem.br\/en\/nuclear-magnetic-resonance-laboratory\/","title":{"rendered":"Nuclear Magnetic Resonance Laboratory"},"content":{"rendered":"

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Nuclear Magnetic Resonance Laboratory<\/span><\/h1>\n

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  3. Nuclear Magnetic Resonance Laboratory<\/span><\/li>\t\t\t\t\t<\/ol>\r\n\t\t\t\t\t
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    About the facility<\/h3>\n

    [\/vc_column_text][vc_column_text css=””]This laboratory focuses on evaluating the structure and activity of proteins and their interactions with small molecules (pharmaceuticals and drugs) or macromolecules (DNA, RNA, and carbohydrates), making it possible to identify modifications in metabolic profiles and potential alterations in metabolic pathways.<\/p>\n

    Nuclear magnetic resonance is an alternative technique that is widely used to resolve the atomic structure of proteins, particularly those with low molecular weights which do not form crystals. This technique offers advantages over crystallography and cryogenic electron microscopy, since it allows researchers to study the dynamics of interactions between proteins and various ligands for samples in solution.[\/vc_column_text][vc_empty_space][vc_column_text]<\/p>\n

    How to submit research proposals<\/h3>\n

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    The Nuclear Magnetic Resonance lab operates on a continuous basis Proposals can be submitted any time during the year, though the SAU Online<\/a>. If you have questions, email the CNPEM User’s Office at edu@cnpem.br<\/a>.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

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    SUBMETA SUA PROPOSTA<\/a><\/h3>\n

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    PREPARE SUA AMOSTRA<\/a><\/h3>\n

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    Equipment<\/span><\/h3>\n

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    Espectr\u00f4metro de Resson\u00e2ncia Magn\u00e9tica Nuclear de 500 MH Agilent DD2<\/h3>\t\t\t\t\t<\/div>\n\t\t<\/span>\n\t<\/a>\n\t\t<\/div>\n\n\t[\/vc_column][vc_column width=”1\/3″]\n\t
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    Espectr\u00f4metro de Resson\u00e2ncia Magn\u00e9tica Nuclear de 600 MHz Agilent INOVA<\/h3>\t\t\t\t\t<\/div>\n\t\t<\/span>\n\t<\/a>\n\t\t<\/div>\n\n\t[\/vc_column][vc_column width=”1\/3″]\n\t
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    Sonda Criog\u00eancia para espectr\u00f4metro de 600 MHz Agilent HNC coldprobe<\/h3>\t\t\t\t\t<\/div>\n\t\t<\/span>\n\t<\/a>\n\t\t<\/div>\n\n\t[\/vc_column][\/vc_row][vc_row full_width=”stretch_row” css=”.vc_custom_1710938879950{background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_column_text css=”.vc_custom_1710875929388{padding-bottom: 2rem !important;}”]<\/p>\n

    Main competencies and techniques<\/h3>\n

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    Sequ\u00eancias de pulso 3D observando ou desacoplando os n\u00facleos<\/h3>\t\t\t\t<\/span>\n\t<\/a>\n\t\t<\/div>\n\n\t[\/vc_column][vc_column width=”1\/3″]\n\t
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    Sequ\u00eancia de pulso 2D para elucida\u00e7\u00e3o estrutural de compostos org\u00e2nicos<\/h3>\t\t\t\t<\/span>\n\t<\/a>\n\t\t<\/div>\n\n\t[\/vc_column][vc_column width=”1\/3″]\n\t
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    Sequ\u00eancia de pulso 1D para fornecer informa\u00e7\u00f5es sobre os complexos de liga\u00e7\u00e3o de prote\u00ednas<\/h3>\t\t\t\t<\/span>\n\t<\/a>\n\t\t<\/div>\n\n\t[\/vc_column][\/vc_row][vc_row full_width=”stretch_row” css=”.vc_custom_1710942543926{background-color: #eff2f5 !important;}”][vc_column][vc_custom_heading text=”meet our team” font_container=”tag:h3|text_align:left” use_theme_fonts=”yes”][vc_row_inner][vc_column_inner width=”1\/4″]
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    Mauricio L. Sfor\u00e7a<\/h2>
    Coordinator<\/div>

    rmn@lnbio.cnpem.br<\/a><\/a>
    \n+55 (19) 3512-1098<\/p><\/div>

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    Silvana Aparecida Rocco<\/h2>
    Researcher<\/div>

    rmn@lnbio.cnpem.br<\/a><\/a>
    \n+55 (19) 3512-1103<\/p><\/div>

    <\/div><\/div><\/div><\/div>[\/vc_column_inner][vc_column_inner width=”1\/4″][\/vc_column_inner][vc_column_inner width=”1\/4″][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” disable_element=”yes” css=”.vc_custom_1714395155864{background-color: #eff2f5 !important;}”][vc_column][vc_custom_heading text=”meet our team” font_container=”tag:h3|text_align:left” use_theme_fonts=”yes”][vc_row_inner][vc_column_inner width=”1\/4″]
    \"\"<\/span><\/div>

    Mauricio L. Sfor\u00e7a<\/h2>
    Coordinator<\/div>

    mauricio.sforca@lnbio.cnpem.br<\/a>
    \n+55 (19) 3512-1098<\/p><\/div>

    <\/div><\/div><\/div><\/div>[\/vc_column_inner][vc_column_inner width=”1\/4″]
    \"\"<\/span><\/div>

    Silvana Aparecida Rocco<\/h2>
    Researcher<\/div>

    silvana.rocco@lnbio.cnpem.br<\/a>
    \n+55 (19) 3512-1103<\/p><\/div>

    <\/div><\/div><\/div><\/div>[\/vc_column_inner][vc_column_inner width=”1\/4″]
    \"\"<\/span><\/div>

    Marcos R. Alborghetti<\/h2>
    Specialist<\/div>

    marcos.alborghetti@lnbio.cnpem.br<\/a>
    \n+55 (19) 3512-1099<\/p><\/div>

    <\/div><\/div><\/div><\/div>[\/vc_column_inner][vc_column_inner width=”1\/4″]
    \"\"<\/span><\/div>

    Irene L. Sousa<\/h2>
    Analyst<\/div>

    irene.sousa@lnbio.cnpem.br<\/a>
    \n+55 (19) 3512-1098<\/p><\/div>

    <\/div><\/div><\/div><\/div>[\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row][vc_column][vc_empty_space][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

    [vc_row full_width=”stretch_row” full_height=”yes” content_placement=”middle” parallax=”content-moving” parallax_image=”51478″ el_class=”fundo-escuro”][vc_column width=”5\/6″][vc_column_text] Nuclear Magnetic Resonance Laboratory [\/vc_column_text][vc_column_text css=”.vc_custom_1696512384777{margin-left: -15px !important;border-left-width: -15px !important;padding-left: -15px !important;}”][\/vc_column_text][\/vc_column][vc_column width=”1\/6″][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” gap=”5″ css=”.vc_custom_1710876484752{padding-top: 4rem !important;padding-bottom: 4rem !important;background-image: url(https:\/\/lnbio.cnpem.br\/wp-content\/uploads\/2024\/03\/grafismo-organico-lnbio-cinza.png?id=35463) !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_column_text] About the facility [\/vc_column_text][vc_column_text css=””]This laboratory focuses on evaluating the structure and activity of proteins and their interactions with…<\/p>\n","protected":false},"author":2,"featured_media":57761,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[63],"tags":[],"class_list":["post-54592","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-instalacoes-abertas","category-63","description-off"],"_links":{"self":[{"href":"https:\/\/lnbio.cnpem.br\/en\/wp-json\/wp\/v2\/posts\/54592","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lnbio.cnpem.br\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lnbio.cnpem.br\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lnbio.cnpem.br\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/lnbio.cnpem.br\/en\/wp-json\/wp\/v2\/comments?post=54592"}],"version-history":[{"count":0,"href":"https:\/\/lnbio.cnpem.br\/en\/wp-json\/wp\/v2\/posts\/54592\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/lnbio.cnpem.br\/en\/wp-json\/wp\/v2\/media\/57761"}],"wp:attachment":[{"href":"https:\/\/lnbio.cnpem.br\/en\/wp-json\/wp\/v2\/media?parent=54592"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lnbio.cnpem.br\/en\/wp-json\/wp\/v2\/categories?post=54592"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lnbio.cnpem.br\/en\/wp-json\/wp\/v2\/tags?post=54592"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}