{"id":52288,"date":"2024-03-15T09:37:39","date_gmt":"2024-03-15T12:37:39","guid":{"rendered":"https:\/\/lnbio.cnpem.br\/divisoes-cientificas\/nucleos-avancados-saude\/imunoterapia-do-cancer\/"},"modified":"2025-10-21T14:13:53","modified_gmt":"2025-10-21T17:13:53","slug":"imunoterapia","status":"publish","type":"page","link":"https:\/\/lnbio.cnpem.br\/en\/divisoes-cientificas\/nucleos-avancados-saude\/imunoterapia\/","title":{"rendered":"Immunotherapy Technology Center (NuTI)"},"content":{"rendered":"

[vc_row full_width=”stretch_row” full_height=”yes” content_placement=”middle” parallax=”content-moving” parallax_image=”57800″ el_class=”fundo-escuro”][vc_column width=”1\/2″][vc_column_text css=””]<\/p>\n

Immunotherapy Technology Center (NuTI)<\/span><\/h1>\n

[\/vc_column_text][vc_column_text css=”.vc_custom_1696512384777{margin-left: -15px !important;border-left-width: -15px !important;padding-left: -15px !important;}”]\t\t\t\r\n\t\t\t

\r\n\r\n\t\t\t\t\r\n\t\t\t\t
\r\n\r\n\t\t\t\t\t\r\n\t\t\t\t\t
    \r\n\t\t\t\t\t\t
  1. \r\n \r\n \r\n \r\n \r\n Home <\/a>\r\n <\/span>\r\n \r\n <\/li>
  2. \/<\/span><\/li>
  3. Immunotherapy Technology Center (NuTI)<\/span><\/li>\t\t\t\t\t<\/ol>\r\n\t\t\t\t\t
    <\/div>\r\n\t\t\t\t<\/div>\r\n\t\t\t<\/div>\r\n\t\t\t[\/vc_column_text][\/vc_column][vc_column width=”1\/2″][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” gap=”5″ css=”.vc_custom_1710932812600{padding-top: 4rem !important;padding-bottom: 4rem !important;background-image: url(https:\/\/lnbio.cnpem.br\/wp-content\/uploads\/2024\/03\/grafismo-organico-lnbio-cinza.png?id=35463) !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_row_inner][vc_column_inner][vc_column_text css=””]Immunotherapy is a clinical mode of treating cancer that complements conventional therapies like surgery, radiation therapy, and chemotherapy. While surgery and radiotherapy are used for local treatment, chemotherapy and immunotherapy are applied systematically.<\/p>\n

    Chemotherapy blocks non-specific mechanisms associated with cell division, while immunotherapy stimulates the immune system to strengthen mechanisms for detecting and eliminating tumor cells.<\/p>\n

    Because of the diversity of types and stages of cancer, many patients do not have a satisfactory response to existing treatments. In this sense, new experimental approaches are being explored such as anti-tumor vaccines, immunomodulating nanoparticles, viral vectors, chimeric aptamers, recombinant proteins, and monoclonal antibodies. The goal of these strategies is lymphocyte co-stimulation and inhibition of immunosuppression mechanisms that antagonize the anti-tumor response.
    \nThese innovative strategies directed at lymphocyte co-stimulation and inhibiting immunosuppression mechanisms demonstrate the potential for developing new therapeutic approaches for cancer.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row][vc_column][vc_empty_space][\/vc_column][\/vc_row][vc_row][vc_column][vc_custom_heading text=”Main findings and scientific publications” font_container=”tag:h3|text_align:left” use_theme_fonts=”yes”][vc_row_inner][vc_column_inner width=”1\/3″]\n\t

    \n\t\n\t\t\t\t
    \n\t\t\t

    Serological Testing for COVID-19, Immunological Surveillance, and Exploration of Protective Antibodies<\/h3>\t\t\t
    Peroni LA, Toscaro JM, Canateli C, Tonoli CCC, de Olivera RR, Benedetti CE, Coimbra LD, Pereira AB, Marques RE, Proen\u00e7a-Modena JL, Lima GC, Viana R, Borges JB, Lin-Wang HT, Abboud CS, Gun C, Franchini KG, Bajgelman MC<\/div>\t\t<\/div>\n\t\t<\/span>\n\t<\/a>\n\n\t\t<\/div>\n\n\t[\/vc_column_inner][vc_column_inner width=”1\/3″]\n\t
    \n\t\n\t\t\t\t
    \n\t\t\t

    Sequential IgG antibody monitoring for virus-inactivated and adenovirus-vectored COVID-19 vaccine in Brazilian healthcare workers<\/h3>\t\t\t
    Lin-Wang HT, Lemes RC, da Silva Farias E, Bajgelman MC, Franchini KG, Viana R, Gun C<\/div>\t\t<\/div>\n\t\t<\/span>\n\t<\/a>\n\n\t\t<\/div>\n\n\t[\/vc_column_inner][vc_column_inner width=”1\/3″]\n\t
    \n\t\n\t\t\t\t
    \n\t\t\t

    Therapeutic BCG vaccine protects against long COVID: The BATTLE randomized clinical trial<\/h3>\t\t\t
    Jalalizadeh M, Buosi K, Giacomelli CF, Leme PAF, Ferrari KL, Dionato FAV, Brito WRS, Brunetti NS, Maia AR, Morari J, Pagliarone AC, Farias AS, Velloso LA, Queiroz MAF, Vallinoto ACR, Bajgelman MC, Reis LO<\/div>\t\t<\/div>\n\t\t<\/span>\n\t<\/a>\n\n\t\t<\/div>\n\n\t[\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” css=”.vc_custom_1696434766725{background-color: #ffffff !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_empty_space height=”32″][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” css=”.vc_custom_1696515988446{background-color: #eff2f5 !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_empty_space height=”16″][vc_custom_heading text=”meet our team” font_container=”tag:h3|text_align:left” use_theme_fonts=”yes” css=””][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” content_placement=”middle” css=”.vc_custom_1696516377387{background-color: #eff2f5 !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column width=”1\/4″]
    \"\"<\/span><\/div>

    Marcio Chaim Bajgelman<\/h2>
    Lead researcher<\/div>

    See Lattes CV<\/a><\/p><\/div>

    <\/div><\/div><\/div><\/div>[\/vc_column][vc_column width=”1\/4″]
    \"\"<\/span><\/div>

    Juliana Branco Novo<\/h2>
    Specialist<\/div>

    See Lattes CV<\/a><\/p><\/div>

    <\/div><\/div><\/div><\/div>[\/vc_column][vc_column width=”1\/4″]
    \"\"<\/span><\/div>

    Luis Antonio Peroni<\/h2>
    Specialist<\/div>

    See Lattes CV<\/a><\/p><\/div>

    <\/div><\/div><\/div><\/div>[\/vc_column][vc_column width=”1\/4″]
    \"\"<\/span><\/div>

    Carolinne Tomarchio Fogagnolo<\/h2>
    Analyst<\/div>

    See Lattes CV<\/a><\/p><\/div>

    <\/div><\/div><\/div><\/div>[\/vc_column][\/vc_row][vc_row full_width=”stretch_row” content_placement=”middle” css=”.vc_custom_1696516377387{background-color: #eff2f5 !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column width=”1\/4″]
    \"\"<\/span><\/div>

    Lucas Stevanin Timoteo<\/h2>
    Analyst<\/div>

    See Lattes CV<\/a><\/p><\/div>

    <\/div><\/div><\/div><\/div>[\/vc_column][vc_column width=”1\/4″]
    \"\"<\/span><\/div>

    Luciana Pereira Ruas<\/h2>
    Analyst<\/div>

    See Lattes CV<\/a><\/p><\/div>

    <\/div><\/div><\/div><\/div>[\/vc_column][vc_column width=”1\/4″][\/vc_column][vc_column width=”1\/4″][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” css=”.vc_custom_1696434766725{background-color: #ffffff !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_empty_space height=”40″][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” css=”.vc_custom_1705339428945{background-color: #ffffff !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_row_inner][vc_column_inner][vc_custom_heading text=”All groups in advanced health technologies” font_container=”tag:h3|text_align:left|color:%23111111″ use_theme_fonts=”yes”][vc_separator color=”green” align=”align_left” border_width=”5″ el_width=”10″ css_animation=”slideInLeft”][vc_empty_space][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” css=”.vc_custom_1710441827678{background-color: #ffffff !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_row_inner][vc_column_inner]