{"id":52287,"date":"2024-03-15T09:29:12","date_gmt":"2024-03-15T12:29:12","guid":{"rendered":"https:\/\/lnbio.cnpem.br\/divisoes-cientificas\/nucleos-avancados-saude\/engenharia-de-tecidos\/"},"modified":"2026-03-20T09:35:46","modified_gmt":"2026-03-20T12:35:46","slug":"engenharia-de-tecidos","status":"publish","type":"page","link":"https:\/\/lnbio.cnpem.br\/en\/divisoes-cientificas\/nucleos-avancados-saude\/engenharia-de-tecidos\/","title":{"rendered":"Tissue Engineering Technology Center (NuTET)"},"content":{"rendered":"

[vc_row full_width=”stretch_row” full_height=”yes” parallax=”content-moving” parallax_image=”51457″ el_class=”fundo-escuro”][vc_column width=”5\/6″][vc_column_text css=””]<\/p>\n

Tissue Engineering Technology Center (NuTET)<\/span><\/h1>\n

[\/vc_column_text][vc_column_text css=”.vc_custom_1696512384777{margin-left: -15px !important;border-left-width: -15px !important;padding-left: -15px !important;}”]\t\t\t\r\n\t\t\t

\r\n\r\n\t\t\t\t\r\n\t\t\t\t
\r\n\r\n\t\t\t\t\t\r\n\t\t\t\t\t
    \r\n\t\t\t\t\t\t
  1. \r\n \r\n \r\n \r\n \r\n Home <\/a>\r\n <\/span>\r\n \r\n <\/li>
  2. \/<\/span><\/li>
  3. Tissue Engineering Technology Center...<\/span><\/li>\t\t\t\t\t<\/ol>\r\n\t\t\t\t\t
    <\/div>\r\n\t\t\t\t<\/div>\r\n\t\t\t<\/div>\r\n\t\t\t[\/vc_column_text][\/vc_column][vc_column width=”1\/6″][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” gap=”5″ css=”.vc_custom_1710932812600{padding-top: 4rem !important;padding-bottom: 4rem !important;background-image: url(https:\/\/lnbio.cnpem.br\/wp-content\/uploads\/2024\/03\/grafismo-organico-lnbio-cinza.png?id=35463) !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_row_inner][vc_column_inner][vc_column_text css=””]The Tissue Engineering Technology Center (NuTET) develops innovative tissue engineering solutions with a focus on regeneration, replacement and repair of human tissues. Using technologies like 3D bioprinting and microphysiological systems, NuTET\u2019s activities range from formulation of biomaterials to creating three-dimensional cell cultures, with applications in regenerative medicine, drug discovery and toxicology.<\/p>\n

    The center works on research that is part of RENAMA (the Brazilian National Network for Alternatives to Animal Testing, an initiative of the Ministry of Science, Technology and Innovation, MCTI), which promotes methods to replace, reduce or improve the use of animals in research, teaching and laboratory testing. Within this context, NuTET develops 3D cell models and platforms such as the ToxChip, which simulates human organs in order to test the safety and efficacy of compounds.<\/p>\n

    NuTET is also investing in the development of biodressings and advanced therapies using personalized biomaterials to treat dermatological conditions, heart disease and eye injuries. All products undergo rigorous physical, chemical and biological testing, following the principles of good practice whenever possible. The center uses a multidisciplinary approach in order to make science more ethical, reproducible and personalized, in line with public policies on health, technological innovation and animal welfare.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row][vc_column][vc_empty_space][\/vc_column][\/vc_row][vc_row][vc_column][vc_custom_heading text=”Main findings and scientific publications” font_container=”tag:h3|text_align:left” use_theme_fonts=”yes”][vc_row_inner][vc_column_inner width=”1\/3″]\n\t

    \n\t\n\t\t\t\t
    \n\t\t\t

    Improving obesity research: Unveiling metabolic pathways through a 3D In vitro model of adipocytes using 3T3-L1 cells<\/h3>\t\t\t
    Thayna Mendonca Avelino, Marta Garc\u00eda-Ar\u00e9valo Provencio, Luis Antonio Peroni, Rom\u00eania Ramos Domingues, Felipe Rafael Torres, Paulo Sergio Lopes de Oliveira, Adriana Franco Paes Leme, Ana Carolina Migliorini Figueira<\/div>\t\t<\/div>\n\t\t<\/span>\n\t<\/a>\n\n\t\t<\/div>\n\n\t[\/vc_column_inner][vc_column_inner width=”1\/3″]\n\t
    \n\t\n\t\t\t\t
    \n\t\t\t

    Unveiling the intricacies of BPA and BPS: Comprehensive insights into its toxic effects using a cutting-edge microphysiological system<\/h3>\t\t\t
    Melissa Dibbernn Ganzerla, Nathalia Indolfo de Carvalho, Larissa Cleres Moreira Oliveira, Tabata Renee Doratioto, Thayn\u00e1 Mendon\u00e7a Avelino, Rafael Junior de Azevedo, Larissa Bueno Tofani, Maiara Ferreira Terra, Giovanna Blazutti Elias, Irene Layane de Sousa, Marcos Rodrigo Alborguetti, Silvana Aparecida Rocco, Kelen Fabiola Arroteia, Ana Carolina Migliorini Figueira<\/div>\t\t<\/div>\n\t\t<\/span>\n\t<\/a>\n\n\t\t<\/div>\n\n\t[\/vc_column_inner][vc_column_inner width=”1\/3″]\n\t
    \n\t\n\t\t\t\t
    \n\t\t\t

    Combining a microphysiological system of three organ equivalents and transcriptomics to assess toxicological endpoints for cosmetic ingredients.<\/h3>\t\t\t
    Nathalia de Carvalho Indolfo, Melissa Dibbernn Ganzerla, T\u00e1bata Ren\u00e9e Doratioto, Thayn\u00e1 Mendon\u00e7a Avelino, Larissa Bueno Tofani, Luis Antonio Peroni, Renata Santos Rabelo, Kelen Fabiola Arroteia, Ana Carolina Migliorini Figueira<\/div>\t\t<\/div>\n\t\t<\/span>\n\t<\/a>\n\n\t\t<\/div>\n\n\t[\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” css=”.vc_custom_1696434766725{background-color: #ffffff !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_empty_space height=”32″][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” css=”.vc_custom_1696515988446{background-color: #eff2f5 !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_empty_space height=”16″][vc_custom_heading text=”meet our team” font_container=”tag:h3|text_align:left” use_theme_fonts=”yes” css=””][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” content_placement=”middle” css=”.vc_custom_1696516377387{background-color: #eff2f5 !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column width=”1\/4″]
    \"\"<\/span><\/div>

    Adriana Paes Leme<\/h2>
    Lead researcher<\/div>

    See Lattes CV<\/a><\/p><\/div>

    <\/div><\/div><\/div><\/div>[\/vc_column][vc_column width=”1\/4″]
    \"\"<\/span><\/div>

    Samarah Vargas Harb<\/h2>
    Adjunct Researcher<\/div>

    See Lattes CV<\/a><\/p><\/div>

    <\/div><\/div><\/div><\/div>[\/vc_column][vc_column width=”1\/4″]
    \"\"<\/span><\/div>

    Cintia Delai da Silva Horinouchi<\/h2>
    Adjunct Researcher<\/div>

    See Lattes CV<\/a><\/p><\/div>

    <\/div><\/div><\/div><\/div>[\/vc_column][vc_column width=”1\/4″]
    \"\"<\/span><\/div>

    Natan Roberto de Barros<\/h2>
    Adjunct Researcher<\/div>

    See Lattes CV<\/a><\/p><\/div>

    <\/div><\/div><\/div><\/div>[\/vc_column][\/vc_row][vc_row full_width=”stretch_row” content_placement=”middle” css=”.vc_custom_1696516377387{background-color: #eff2f5 !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column width=”1\/4″]
    \"\"<\/span><\/div>

    Ana Carolina de Aguiar<\/h2>
    Analyst<\/div>

    See Lattes CV<\/a><\/p><\/div>

    <\/div><\/div><\/div><\/div>[\/vc_column][vc_column width=”1\/4″]
    \"\"<\/span><\/div>

    Giovanna Blazutti Elias<\/h2>
    Analyst<\/div>

    See Lattes CV<\/a><\/p><\/div>

    <\/div><\/div><\/div><\/div>[\/vc_column][vc_column width=”1\/4″]
    \"\"<\/span><\/div>

    Ingrid Iara Damas<\/h2>
    Analyst<\/div>

    See Lattes CV<\/a><\/p><\/div>

    <\/div><\/div><\/div><\/div>[\/vc_column][vc_column width=”1\/4″]
    \"\"<\/span><\/div>

    Larissa Cleres Moreira Oliveira<\/h2>
    Analyst<\/div>

    See Lattes CV<\/a><\/p><\/div>

    <\/div><\/div><\/div><\/div>[\/vc_column][\/vc_row][vc_row full_width=”stretch_row” css=”.vc_custom_1696434766725{background-color: #ffffff !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_empty_space height=”40″][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” css=”.vc_custom_1705339428945{background-color: #ffffff !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_row_inner][vc_column_inner][vc_custom_heading text=”All groups in advanced health technologies” font_container=”tag:h3|text_align:left|color:%23111111″ use_theme_fonts=”yes”][vc_separator color=”green” align=”align_left” border_width=”5″ el_width=”10″ css_animation=”slideInLeft”][vc_empty_space][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” css=”.vc_custom_1710441827678{background-color: #ffffff !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_row_inner][vc_column_inner]