{"id":52277,"date":"2024-03-14T16:03:32","date_gmt":"2024-03-14T19:03:32","guid":{"rendered":"https:\/\/lnbio.cnpem.br\/divisoes-cientificas\/biologia-integrativa\/condensados-biomoleculares\/"},"modified":"2025-10-21T11:33:14","modified_gmt":"2025-10-21T14:33:14","slug":"organelas-nao-membranosas","status":"publish","type":"page","link":"https:\/\/lnbio.cnpem.br\/en\/divisoes-cientificas\/biologia-integrativa\/organelas-nao-membranosas\/","title":{"rendered":"Non-Membrane Organelles"},"content":{"rendered":"

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Non-Membrane Organelles<\/span><\/h1>\n

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  3. Non-Membrane Organelles<\/span><\/li>\t\t\t\t\t<\/ol>\r\n\t\t\t\t\t
    <\/div>\r\n\t\t\t\t<\/div>\r\n\t\t\t<\/div>\r\n\t\t\t[\/vc_column_text][\/vc_column][vc_column width=”1\/6″][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” gap=”5″ css=”.vc_custom_1710932812600{padding-top: 4rem !important;padding-bottom: 4rem !important;background-image: url(https:\/\/lnbio.cnpem.br\/wp-content\/uploads\/2024\/03\/grafismo-organico-lnbio-cinza.png?id=35463) !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_row_inner][vc_column_inner][vc_column_text css=””]Non-membrane organelles are cellular structures that do not have a lipoprotein membrane surrounding them. Most of these organelles are made up of biomolecular condensates composed of proteins and nucleic acids, and play fundamental roles in regulating complex biological processes and maintaining cellular functions.<\/p>\n

    With advanced techniques in molecular, cellular and structural biology, LNBio stands out in research on the molecular mechanisms that regulate the function of these organelles. This group also works to identify small molecules that can modulate the functions of these proteins, and understand how they affect the formation of biomolecular condensates.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row][vc_column][vc_empty_space][\/vc_column][\/vc_row][vc_row][vc_column][vc_custom_heading text=”Main findings and scientific publications” font_container=”tag:h3|text_align:left” use_theme_fonts=”yes”][vc_row_inner][vc_column_inner width=”1\/3″]\n\t

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    A comprehensive review on DDX3X liquid phase condensation in health and neurodevelopmental disorders<\/h3>\t\t\t
    Ivan Rosa e Silva, Juliana Helena Costa Smetana & Juliana Ferreira de Oliveira<\/div>\t\t<\/div>\n\t\t<\/span>\n\t<\/a>\n\n\t\t<\/div>\n\n\t[\/vc_column_inner][vc_column_inner width=”1\/3″]\n\t
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    A computational pipeline for image-based statistical analysis of biomolecular condensates dynamics using morphological descriptors<\/h3>\t\t\t
    Ivan Rosa e Silva, Guilherme Gurian Dariani, Felipe Zanghelini Benevenutti, Renata Rocha de Oliveira, Vit\u00f3ria Yumi Uetuki Nicoleti & Murilo de Carvalho<\/div>\t\t<\/div>\n\t\t<\/span>\n\t<\/a>\n\n\t\t<\/div>\n\n\t[\/vc_column_inner][vc_column_inner width=”1\/3″][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” css=”.vc_custom_1696434766725{background-color: #ffffff !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_empty_space height=”32″][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” css=”.vc_custom_1696515988446{background-color: #eff2f5 !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” content_placement=”middle” css=”.vc_custom_1696516377387{background-color: #eff2f5 !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column width=”1\/4″][vc_custom_heading text=”meet
    \nour team” font_container=”tag:h3|text_align:left” use_theme_fonts=”yes”][\/vc_column][vc_column width=”1\/4″]
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    Ivan Rosa e Silva<\/h2>
    Lead Researcher<\/div>

    See Lattes CV<\/a><\/p><\/div>

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    Felipe Zanghelini Benevenutti<\/h2>
    Technological Development Analyst<\/div>

    See Lattes CV<\/a><\/p><\/div>

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    Mariana Rodrigues da Silva<\/h2>
    Technological Development Analyst<\/div>

    See Lattes CV<\/a><\/p><\/div>

    <\/div><\/div><\/div><\/div>[\/vc_column][\/vc_row][vc_row full_width=”stretch_row” css=”.vc_custom_1696434766725{background-color: #ffffff !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_empty_space height=”40″][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” css=”.vc_custom_1705339428945{background-color: #ffffff !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_row_inner][vc_column_inner][vc_custom_heading text=”All groups in integrative biology” font_container=”tag:h3|text_align:left|color:%23111111″ use_theme_fonts=”yes”][vc_separator color=”green” align=”align_left” border_width=”5″ el_width=”10″ css_animation=”slideInLeft”][vc_empty_space][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” css=”.vc_custom_1710441827678{background-color: #ffffff !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_row_inner][vc_column_inner]