{"id":52269,"date":"2024-01-15T14:05:01","date_gmt":"2024-01-15T17:05:01","guid":{"rendered":"https:\/\/lnbio.cnpem.br\/divisoes-cientificas\/imunidade-e-patogenos\/virologia\/"},"modified":"2025-11-06T14:54:51","modified_gmt":"2025-11-06T17:54:51","slug":"virologia","status":"publish","type":"page","link":"https:\/\/lnbio.cnpem.br\/en\/divisoes-cientificas\/imunidade-e-patogenos\/virologia\/","title":{"rendered":"Virology"},"content":{"rendered":"

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Virology<\/span><\/h1>\n

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  3. Virology<\/span><\/li>\t\t\t\t\t<\/ol>\r\n\t\t\t\t\t
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    The study of viral proteins provides a more comprehensive understanding of virus biology, which is essential for the development of treatments, diagnostic methods and vaccines. Arboviruses (which are transmitted by arthropods like mosquitoes) are a global health problem that has worsened with climate change. Diseases like dengue, zika, chikungunya, and various other less-studied arbovirus diseases require a modern, high-tech approach that offers crucial insights for developing solutions to reduce the impact of these emerging diseases and strengthen our preparations against the viral diseases of the future.<\/p>\n

    Within this context, the Virology Group directs its efforts toward revealing and analyzing viral proteins, using technical approaches that range from basic virology to sophisticated microscopy, advanced molecular biology techniques and mass spectrometry. These tools make it possible to identify molecular targets and develop effective therapeutic solutions against emerging arboviruses, which rarely have means of control or prevention, to protect public health.<\/p>\n

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    Cryo-EM structure of the mature and infective Mayaro virus at 4.4\u2009\u00c5 resolution reveals features of arthritogenic alphaviruses<\/h3>\t\t\t
    Ribeiro-Filho, H.V., Coimbra, L.D., Cassago, A. et al.<\/div>\t\t<\/div>\n\t\t<\/span>\n\t<\/a>\n\n\t\t<\/div>\n\n\t[\/vc_column_inner][vc_column_inner width=”1\/3″]\n\t
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    Lysergol exerts potent antiviral activity against the emerging Oropouche virus in vitro<\/h3>\t\t\t
    Coimbra LD, Shimizu JF, Nagai A, Borin A, Fontoura MA, Concha JO, Leme L, Lucas do Carmo K, de Oliveira LC, Soprano AS, Felipe JS, Silva AB, Forato J, Scachetti GC, Crump CM, Sacchetto L, Nogueira ML, Bezerra EHS, Guimar\u00e3es SL, Cordeiro AT, Proen\u00e7a-Modena JL, daSilva LLP, Boratto PVM, Melo Hanchuk TD, Marques RE<\/div>\t\t<\/div>\n\t\t<\/span>\n\t<\/a>\n\n\t\t<\/div>\n\n\t[\/vc_column_inner][vc_column_inner width=”1\/3″]\n\t
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    A central role for CCR2 in monocyte recruitment and blood-brain barrier disruption during Usutu virus encephalitis. J Neuroinflammation<\/h3>\t\t\t
    Slowikowski E, Willems C, Lemes RMR, Schuermans S, Berghmans N, Rocha RPF, Martens E, Proost P, Delang L, Marques RE, Filho JCA, Marques PE<\/div>\t\t<\/div>\n\t\t<\/span>\n\t<\/a>\n\n\t\t<\/div>\n\n\t[\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” css=”.vc_custom_1696434766725{background-color: #ffffff !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_empty_space height=”32″][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” css=”.vc_custom_1696515988446{background-color: #eff2f5 !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_custom_heading text=”meet our team” font_container=”tag:h3|text_align:left” use_theme_fonts=”yes” css=””][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” content_placement=”middle” css=”.vc_custom_1696516377387{background-color: #eff2f5 !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column width=”1\/4″]
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    Rafael Elias Marques<\/h2>
    Lead Researcher<\/div>

    See Lattes CV<\/a><\/p><\/div>

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    Eduardo Henrique Salviano Bezerra<\/h2>
    Adjunct Researcher<\/div>

    See Lattes CV<\/a><\/p><\/div>

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    Paulo Victor de Miranda Boratto<\/h2>
    Adjunct Researcher<\/div>

    See Lattes CV<\/a><\/p><\/div>

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    Samuel Leite Guimar\u00e3es<\/h2>
    Adjunct Researcher<\/div>

    See Lattes CV<\/a><\/p><\/div>

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    Talita Diniz Melo Hanchuk<\/h2>
    Adjunct Researcher<\/div>

    See Lattes CV<\/a><\/p><\/div>

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    Adriana Santos Soprano<\/h2>
    Specialist<\/div>

    See Lattes CV<\/a><\/p><\/div>

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    Lais Durco Coimbra<\/h2>
    Specialist<\/div>

    See Lattes CV<\/a><\/p><\/div>

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    Leonardo Camilo de Oliveira<\/h2>
    Specialist<\/div>

    See Lattes CV<\/a><\/p><\/div>

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    Marina Alves Fontoura<\/h2>
    Specialist<\/div>

    See Lattes CV<\/a><\/p><\/div>

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    Nayanne Loiuse Costacurta Polli<\/h2>
    Specialist<\/div>

    See Lattes CV<\/a><\/p><\/div>

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    Alice Nagai<\/h2>
    Analyst<\/div>

    See Lattes CV<\/a><\/p><\/div>

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    Jaqueline Farinha Shimizu<\/h2>
    Analyst<\/div>

    See Lattes CV<\/a><\/p><\/div>

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    Valber Florencio Ferreira<\/h2>
    Analyst<\/div>

    See Lattes CV<\/a><\/p><\/div>

    <\/div><\/div><\/div><\/div>[\/vc_column][vc_column width=”1\/4″][\/vc_column][vc_column width=”1\/4″][\/vc_column][vc_column width=”1\/4″][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” css=”.vc_custom_1696434766725{background-color: #ffffff !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_empty_space height=”40″][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” css=”.vc_custom_1705339428945{background-color: #ffffff !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_row_inner][vc_column_inner][vc_custom_heading text=”All groups in immunity and pathogens” font_container=”tag:h3|text_align:left|color:%23111111″ use_theme_fonts=”yes”][vc_separator color=”green” align=”align_left” border_width=”5″ el_width=”10″ css_animation=”slideInLeft”][vc_empty_space][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” css=”.vc_custom_1710441827678{background-color: #ffffff !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_row_inner][vc_column_inner]