{"id":52236,"date":"2024-03-15T16:03:54","date_gmt":"2024-03-15T19:03:54","guid":{"rendered":"https:\/\/lnbio.cnpem.br\/divisoes-cientificas\/facilities-servicos\/advanced-methods-in-biology\/"},"modified":"2025-11-06T15:00:23","modified_gmt":"2025-11-06T18:00:23","slug":"metodologias-avancadas-em-biologia","status":"publish","type":"page","link":"https:\/\/lnbio.cnpem.br\/en\/divisoes-cientificas\/facilities-servicos\/metodologias-avancadas-em-biologia\/","title":{"rendered":"Advanced Methods in Biology"},"content":{"rendered":"

[vc_row full_width=”stretch_row” full_height=”yes” content_placement=”middle” parallax=”content-moving” parallax_image=”57739″ el_class=”fundo-escuro”][vc_column][vc_custom_heading text=”Advanced Methods in Biology” font_container=”tag:h1|text_align:left|color:%23ffffff” use_theme_fonts=”yes” css=””][vc_column_text css=”.vc_custom_1696512384777{margin-left: -15px !important;border-left-width: -15px !important;padding-left: -15px !important;}”]\t\t\t\r\n\t\t\t

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  3. Advanced Methods in Biology<\/span><\/li>\t\t\t\t\t<\/ol>\r\n\t\t\t\t\t
    <\/div>\r\n\t\t\t\t<\/div>\r\n\t\t\t<\/div>\r\n\t\t\t[\/vc_column_text][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” bg_type=”grad” css=”.vc_custom_1696869286027{background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}” bg_grad=”background: -webkit-gradient(linear, left top, left bottom, color-stop(0%, #02735E), color-stop(99%, #009DA8));background: -moz-linear-gradient(left,#02735E 0%,#009DA8 99%);background: -webkit-linear-gradient(left,#02735E 0%,#009DA8 99%);background: -o-linear-gradient(left,#02735E 0%,#009DA8 99%);background: -ms-linear-gradient(left,#02735E 0%,#009DA8 99%);background: linear-gradient(left,#02735E 0%,#009DA8 99%);”][vc_column css=”.vc_custom_1695215965337{padding-top: 28px !important;padding-bottom: 28px !important;}”][vc_empty_space][vc_custom_heading text=”Advanced Methods in Biology” font_container=”tag:h3|text_align:left|color:%23ffffff” use_theme_fonts=”yes” css=””][vc_column_text css=””]The bioimaging, advanced omics and biological data groups offer tools to advance modern biology. Bioimaging allows high-resolution visualization of biological structures and processes at the molecular, cellular, and tissue level, revealing details about the dynamics and function of these systems. Advanced omics represents an integrated and highly complex approach to investigating biological systems at the molecular level. This includes technologies such as transcriptomics, proteomics, metabolomics, epigenomics and interatomics, allowing comprehensive and simultaneous analysis of different layers of cell regulation.<\/span><\/p>\n

    Techniques like flow cytometry and cell sorting are fundamental to this process, permitting precise identification and isolation of specific cell subpopulations from heterogeneous samples and enabling more sensitive omics analyses, reducing experimental noise and making it possible to investigate biological events on an individual scale.<\/span><\/p>\n

    Finally, bioinformatics works as a set of sophisticated computational tools dedicated to integrating data using intelligent algorithms to analyze, interpret, and extract information from enormous datasets generated by modern technologies like bioimaging and omics. Advanced methodologies have the potential to revolutionize our understanding of biological processes in health and in illnesses, creating new opportunities for early diagnosis, the development of personalized therapies, and to discover prognostic biomarkers.<\/span>[\/vc_column_text][vc_empty_space][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” css=”.vc_custom_1696434766725{background-color: #ffffff !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_empty_space height=”40″][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” css=”.vc_custom_1696434766725{background-color: #ffffff !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column width=”1\/4″]

    \"null\"

    Biological Imaging Laboratory<\/h3>

    Learn more about LIB<\/p><\/div><\/div><\/a><\/div>[vc_column_text css=””]The<\/span><\/span><\/span> laboratory<\/span><\/span><\/span> uses<\/span><\/span><\/span> conventional<\/span><\/span><\/span> methods<\/span><\/span><\/span> with<\/span><\/span><\/span> visible<\/span><\/span><\/span> light<\/span><\/span><\/span> bright<\/span><\/span><\/span> field<\/span><\/span><\/span> and<\/span><\/span><\/span> phase<\/span><\/span><\/span> contrast<\/span><\/span><\/span> microscopy<\/span><\/span><\/span>, <\/span><\/span>as<\/span><\/span><\/span> well<\/span><\/span><\/span> as<\/span><\/span><\/span> confocal<\/span><\/span><\/span> laser<\/span><\/span><\/span> and<\/span><\/span><\/span> super<\/span><\/span><\/span>–<\/span><\/span>resolution<\/span><\/span><\/span> microscopy<\/span><\/span><\/span> for<\/span><\/span><\/span> studies<\/span><\/span><\/span> of<\/span><\/span><\/span> cell<\/span><\/span><\/span> morphology<\/span><\/span><\/span>, <\/span><\/span>specific<\/span><\/span><\/span> labeling<\/span><\/span><\/span> of<\/span><\/span><\/span> organelles<\/span><\/span><\/span>, <\/span><\/span>proteins<\/span><\/span><\/span>, <\/span><\/span>and<\/span><\/span><\/span> nucleic<\/span><\/span><\/span> acid<\/span><\/span><\/span> sequences<\/span><\/span><\/span>[\/vc_column_text][vc_empty_space height=”10px”][vc_empty_space height=”10px”][\/vc_column][vc_column width=”1\/4″]

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    Biological Data<\/h3>

    Learn more about Biological Data<\/p><\/div><\/div><\/a><\/div>[vc_column_text css=””]The<\/span><\/span> team<\/span><\/span> develops<\/span><\/span> and<\/span><\/span> performs<\/span><\/span> advanced<\/span><\/span> computational<\/span><\/span> analyses<\/span><\/span> and<\/span><\/span> supports<\/span><\/span> the<\/span><\/span> infrastructure<\/span><\/span> for<\/span><\/span> storing<\/span><\/span> and<\/span><\/span> processing<\/span><\/span> a<\/span><\/span> wide<\/span><\/span> variety<\/span><\/span> of<\/span><\/span> biological<\/span><\/span> data<\/span><\/span>[\/vc_column_text][vc_empty_space height=”10px”][vc_empty_space height=”10px”][\/vc_column][vc_column width=”1\/4″]

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    Advanced Omics Laboratory<\/h3>

    Learn more about Advanced Omics Laboratory<\/p><\/div><\/div><\/a><\/div>[vc_column_text css=””]A multidisciplinary space dedicated to sample processing for omics applications, integrating flow cytometry technologies, high-precision cell sorting and single-cell analysis[\/vc_column_text][vc_empty_space height=”10px”][vc_empty_space height=”10px”][\/vc_column][vc_column width=”1\/4″][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” css=”.vc_custom_1696515988446{background-color: #eff2f5 !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_empty_space height=”16″][vc_custom_heading text=”meet our team” font_container=”tag:h3|text_align:left” use_theme_fonts=”yes” css=””][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” content_placement=”middle” css=”.vc_custom_1696516377387{background-color: #eff2f5 !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column width=”1\/4″]

    \"\"<\/span><\/div>

    Juliana Ferreira Oliveira<\/h2>
    Lead Researcher<\/div>
    <\/div><\/div><\/div><\/div>[\/vc_column][vc_column width=”1\/4″]
    \"\"<\/span><\/div>

    Jos\u00e9 Edwin Neciosup Ques\u00f1ay<\/h2>
    Specialist<\/div>
    <\/div><\/div><\/div><\/div>[\/vc_column][vc_column width=”1\/4″][\/vc_column][vc_column width=”1\/4″][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” disable_element=”yes” css=”.vc_custom_1714395328545{background-color: #ffffff !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column width=”1\/3″]
    \"null\"

    Laborat\u00f3rio de imagens biol\u00f3gicas<\/h3>

    Descubra o laborat\u00f3rio de imagens biol\u00f3gicas<\/p><\/div><\/div><\/a><\/div>[vc_column_text]Laborat\u00f3rio utiliza m\u00e9todos convencionais com luz vis\u00edvel de campo claro e contraste de fase at\u00e9 microscopias confocal a laser e de super resolu\u00e7\u00e3o para estudos de morfologia celular, marca\u00e7\u00f5es espec\u00edficas de organelas, prote\u00ednas e sequ\u00eancias de \u00e1cidos nucl\u00e9icos[\/vc_column_text][vc_empty_space height=”10px”][vc_empty_space height=”10px”][\/vc_column][vc_column width=”1\/3″]

    \"null\"

    Laborat\u00f3rio de bioinform\u00e1tica<\/h3>

    Descubra o laborat\u00f3rio de bioinform\u00e1tica<\/p><\/div><\/div><\/a><\/div>[vc_column_text]Lorem ipsum dolor sit amet, consectetur adipiscing elit. Aliquam bibendum luctus diam vitae laoreet. Nullam finibus enim sapien, a tristique urna sollicitudin commodo[\/vc_column_text][vc_empty_space height=”10px”][vc_empty_space height=”10px”][\/vc_column][vc_column width=”1\/3″]

    \"null\"

    Laborat\u00f3rio de \u00f4micas avan\u00e7adas<\/h3>

    Descubra o laborat\u00f3rio de \u00f4micas avan\u00e7adas<\/p><\/div><\/div><\/a><\/div>[vc_column_text]Lorem ipsum dolor sit amet, consectetur adipiscing elit. Aliquam bibendum luctus diam vitae laoreet. Nullam finibus enim sapien, a tristique urna sollicitudin commodo[\/vc_column_text][vc_empty_space height=”10px”][vc_empty_space height=”10px”][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” disable_element=”yes” css=”.vc_custom_1710519645378{background-color: #eff2f5 !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_custom_heading text=”conhe\u00e7a nossa equipe”][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” content_placement=”middle” disable_element=”yes” css=”.vc_custom_1710519651822{background-color: #eff2f5 !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column width=”1\/4″]

    \"\"<\/span><\/div>

    Juliana Ferreira Oliveira<\/h2>
    L\u00edder de divis\u00e3o<\/div>
    <\/div><\/div><\/div><\/div>[\/vc_column][vc_column width=”1\/4″]
    \"\"<\/span><\/div>

    Celisa Caldana Tofoli<\/h2>
    Especialista l\u00edder<\/div>

    grupo de biomol\u00e9culas<\/strong>
    \nVer curr\u00edculo Lattes<\/a><\/p><\/div>

    <\/div><\/div><\/div><\/div>[\/vc_column][vc_column width=”1\/4″]
    \"\"<\/span><\/div>

    Mauricio Sfor\u00e7a<\/h2>
    Especialista l\u00edder<\/div>

    grupo espectroscopia anal\u00edtica<\/strong>
    \nVer curr\u00edculo Lattes<\/a><\/p><\/div>

    <\/div><\/div><\/div><\/div>[\/vc_column][vc_column width=”1\/4″]
    \"\"<\/span><\/div>

    Juliana Ferreira Oliveira<\/h2>
    Pesquisadora l\u00edder (interina)<\/div>

    grupo de metodologias avan\u00e7adas em biologia<\/strong>
    \nVer curr\u00edculo Lattes<\/a><\/p><\/div>

    <\/div><\/div><\/div><\/div>[\/vc_column][\/vc_row][vc_row full_width=”stretch_row” content_placement=”middle” disable_element=”yes” css=”.vc_custom_1710519658518{background-color: #eff2f5 !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column width=”1\/4″]
    \"\"<\/span><\/div>

    Juliana Ferreira Oliveira<\/h2>
    Pesquisadora l\u00edder<\/div>

    grupo de bioensaios<\/strong>
    \nVer curr\u00edculo Lattes<\/a><\/p><\/div>

    <\/div><\/div><\/div><\/div>[\/vc_column][vc_column width=”1\/4″][\/vc_column][vc_column width=”1\/4″][\/vc_column][vc_column width=”1\/4″][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” disable_element=”yes” css=”.vc_custom_1710519666862{background-color: #ffffff !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_empty_space height=”40″][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” disable_element=”yes” css=”.vc_custom_1710519672666{background: #ffffff url(https:\/\/lnbio.cnpem.br\/wp-content\/uploads\/2023\/10\/padrao-bg-estreito-lnbio-pesquisa-e-desenvolvimento-tecnologias-para-saude-6.png?id=7665) !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column width=”1\/4″][vc_empty_space height=”10px”][vc_custom_heading text=”veja
    \nmais
    \ndivis\u00f5es
    \ncient\u00edficas” font_container=”tag:h2|text_align:left|color:%23ffffff”][\/vc_column][vc_column width=”1\/4″][vc_empty_space height=”10px”][vc_custom_heading text=”Biologia integrativa” font_container=”tag:h4|text_align:left|color:%23ffffff”][vc_separator color=”custom” align=”align_left” border_width=”5″ el_width=”10″ css_animation=”none” accent_color=”#ffffff”][vc_empty_space height=”10px”][vc_column_text]<\/p>\n

    Pesquisas em tr\u00eas principais campos: c\u00e2ncer de cabe\u00e7a e pesco\u00e7o, c\u00e2ncer de mama e estrat\u00e9gias de imunomodula\u00e7\u00e3o para potencializar a resposta antitumoral<\/span><\/p>\n

    [\/vc_column_text][vc_empty_space height=”10px”][vc_column_text]<\/p>\n

    DESCUBRA \u21fe<\/a><\/span><\/h5>\n

    [\/vc_column_text][vc_empty_space height=”10px”][\/vc_column][vc_column width=”1\/4″][vc_empty_space height=”10px”][vc_custom_heading text=”Imunidade e pat\u00f3genos” font_container=”tag:h4|text_align:left|color:%23ffffff”][vc_separator color=”custom” align=”align_left” border_width=”5″ el_width=”10″ css_animation=”none” accent_color=”#ffffff”][vc_empty_space height=”10px”][vc_column_text]<\/p>\n

    Pesquisas em tr\u00eas principais campos: c\u00e2ncer de cabe\u00e7a e pesco\u00e7o, c\u00e2ncer de mama e estrat\u00e9gias de imunomodula\u00e7\u00e3o para potencializar a resposta antitumoral<\/span><\/p>\n

    [\/vc_column_text][vc_empty_space height=”10px”][vc_column_text]<\/p>\n

    DESCUBRA \u21fe<\/a><\/span><\/h5>\n

    [\/vc_column_text][vc_empty_space height=”10px”][\/vc_column][vc_column width=”1\/4″][vc_empty_space height=”10px”][vc_custom_heading text=”N\u00facleos avan\u00e7ados de tecnologias em sa\u00fade” font_container=”tag:h4|text_align:left|color:%23ffffff”][vc_separator color=”custom” align=”align_left” border_width=”5″ el_width=”10″ css_animation=”none” accent_color=”#ffffff”][vc_empty_space height=”10px”][vc_column_text]<\/p>\n

    T\u00e9cnicas de biologia molecular, celular, estrutural e modelos gen\u00e9ticos modificados para investigar os mecanismos moleculares relacionados \u00e0 Defici\u00eancia Intelectual<\/span><\/p>\n

    [\/vc_column_text][vc_empty_space height=”10px”][vc_column_text]<\/p>\n

    DESCUBRA \u21fe<\/a><\/span><\/h5>\n

    [\/vc_column_text][vc_empty_space height=”10px”][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” css=”.vc_custom_1696434766725{background-color: #ffffff !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column][vc_empty_space height=”40″][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

    [vc_row full_width=”stretch_row” full_height=”yes” content_placement=”middle” parallax=”content-moving” parallax_image=”57739″ el_class=”fundo-escuro”][vc_column][vc_custom_heading text=”Advanced Methods in Biology” font_container=”tag:h1|text_align:left|color:%23ffffff” use_theme_fonts=”yes” css=””][vc_column_text css=”.vc_custom_1696512384777{margin-left: -15px !important;border-left-width: -15px !important;padding-left: -15px !important;}”][\/vc_column_text][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” bg_type=”grad” css=”.vc_custom_1696869286027{background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}” bg_grad=”background: -webkit-gradient(linear, left top, left bottom, color-stop(0%, #02735E), color-stop(99%, #009DA8));background: -moz-linear-gradient(left,#02735E 0%,#009DA8 99%);background: -webkit-linear-gradient(left,#02735E 0%,#009DA8 99%);background: -o-linear-gradient(left,#02735E 0%,#009DA8 99%);background: -ms-linear-gradient(left,#02735E 0%,#009DA8 99%);background: linear-gradient(left,#02735E 0%,#009DA8 99%);”][vc_column…<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":52232,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[131,127,126],"tags":[],"class_list":["post-52236","page","type-page","status-publish","hentry","category-advanced-methods-in-biology","category-facilities-and-services","category-scientific-divisions","description-off"],"_links":{"self":[{"href":"https:\/\/lnbio.cnpem.br\/en\/wp-json\/wp\/v2\/pages\/52236","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lnbio.cnpem.br\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/lnbio.cnpem.br\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/lnbio.cnpem.br\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/lnbio.cnpem.br\/en\/wp-json\/wp\/v2\/comments?post=52236"}],"version-history":[{"count":0,"href":"https:\/\/lnbio.cnpem.br\/en\/wp-json\/wp\/v2\/pages\/52236\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/lnbio.cnpem.br\/en\/wp-json\/wp\/v2\/pages\/52232"}],"wp:attachment":[{"href":"https:\/\/lnbio.cnpem.br\/en\/wp-json\/wp\/v2\/media?parent=52236"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lnbio.cnpem.br\/en\/wp-json\/wp\/v2\/categories?post=52236"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lnbio.cnpem.br\/en\/wp-json\/wp\/v2\/tags?post=52236"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}