Available services and technologies
Model Organisms Laboratory (LOM)
The Model Organisms Laboratory at LNBio/CNPEM produces transgenic, knockout and knockin mice using classical transgenic tools and the latest CRISPR/Cas9 technology. It also provides training in CRISPR/Cas9 either to generate genetically modified cell lines or mice.
Available services and technologies:
– Generation of transgenic mouse line through classical pronuclear injection.
– Generation of knockout or knockin mouse line through (1) injection of CRISPR/Cas9 tool into zygote pronucleus or (2) injection of genetically modified mouse embryonic stem cells into murine blastocyst.
– Training in CRISPR/Cas9 technology